Excipients and Drug Formulation Canada

Excipients and Drug Formulation

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An excipient is a pharmacologically inactive substance formulated alongside the active pharmaceutical ingredient of a medication. Purposes served by excipients:

Provide bulk to the formulation
Facilitate drug absorption or solubility and other pharmacokinetic considerations.
Aid in handling of “API” during manufacturing.
Provide stability and prevent from denaturation.
Excipients has No interaction with drug. Pharmacologically inert. Feasible .

A list of Pharmaceutical Excipients used in pharmaceutical preparations usually: Fillers. Binders. Disintegrants. Coatings. Sorbents. Antiadherent. Lubricants. Glidants. Preservatives. Antioxidants. Flavoring Agents. Sweeting Agents. Coloring Agents. Solvent & Co-solvent. Buffering Agents. Chelating Agents. Viscosity imparting Agents. Surface Active Agents. Humectants .

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