NORTH AMERICA Excipients and Drug Formulation

Excipients and Drug Formulation

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An excipient is a pharmacologically inactive substance formulated alongside the active pharmaceutical ingredient of a medication. Purposes served by excipients:

  • Provide bulk to the formulation
  • Facilitate drug absorption or solubility and other pharmacokinetic considerations.
  • Aid in handling of “API” during manufacturing.
  • Provide stability and prevent from denaturation.
  • Excipients has No interaction with drug. Pharmacologically inert. Feasible .

A list of Pharmaceutical Excipients used in pharmaceutical preparations usually: Fillers. Binders. Disintegrants. Coatings. Sorbents. Antiadherent. Lubricants. Glidants. Preservatives. Antioxidants. Flavoring Agents. Sweeting Agents. Coloring Agents. Solvent & Co-solvent. Buffering Agents. Chelating Agents. Viscosity imparting Agents. Surface Active Agents. Humectants .

Antioxidants

Capsules/Encapsulation

Catalyst

Coating Agents

Coating Material

Colour and Dispersion

Correctives

Disintegrants

Drug Delivery Systems

Emulsifying/Solubilizing Agents

Essence

Excipient

Filtering Aid

Fining Agent

Flavours and Perfumes

Formulation Development

Glidants

Lubricants

Menstruum

Microencapsulation

Ointments Bases

Opacifier

Other Excipients/Drug Formulation

Ph Control Agents

Plasticizer

Preservative

Solvents

Stabilizing Agent

Stiffening Agents

Suppository Bases

Surfactant

Suspending/Viscosity Increasing Agents

Sweetening Agents

Tablet Binders

Tablet Disintegrants

Tablet Filler-Binders

Transdermal Enhancers

Wetting/Solubilising Agents


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